| Rank | Median Household Income ▼ | School District / Population |
| 1. | $60,962 | Pemiscot County R-3 School District / 1,080 |
| 2. | $52,885 | Leopold R-III School District / 1,040 |
| 3. | $49,375 | Oran R-III School District / 2,226 |
| 4. | $44,917 | Delta C-7 School District / 799 |
| 5. | $44,236 | Scott County R-IV School District / 6,061 |
| 6. | $43,295 | Risco R-II School District / 637 |
| 7. | $42,500 | Marmaduke School District / 3,809 |
| 8. | $41,923 | Scott County Central Schools / 2,003 |
| 9. | $41,523 | Greene County Technical School District / 18,108 |
| 10. | $41,393 | Van Buren R-I School District / 3,445 |
| 11. | $41,250 | Advance R-IV School District / 3,072 |
| 12. | $41,172 | Delta R-V School District / 2,127 |
| 13. | $40,273 | Bloomfield School District / 4,568 |
| 14. | $40,227 | Richland R-I School District / 1,711 |
| 15. | $39,840 | Bernie School District / 3,142 |
| 16. | $39,807 | Pocahontas School District / 11,616 |
| 17. | $39,375 | Puxico R-VIII School District / 4,567 |
| 18. | $38,750 | Ripley County R-III School District / 854 |
| 18. | $38,750 | Rector School District / 4,281 |
| 20. | $38,393 | Maynard School District / 2,924 |
| 21. | $37,421 | Dexter R-XI School District / 12,886 |
| 22. | $37,413 | Senath-Hornersville C-8 School District / 4,750 |
| 23. | $37,337 | Sikeston School District / 20,851 |
| 24. | $37,241 | Holcomb R-III School District / 2,342 |
| 25. | $37,222 | Portageville School District / 4,170 |
| 26. | $36,842 | Bell City R-II School District / 1,410 |
| 27. | $36,328 | Poplar Bluff R-I School District / 31,675 |
| 28. | $35,349 | Neelyville R-IV School District / 4,558 |
| 29. | $34,965 | Paragould School District / 21,372 |
| 30. | $34,643 | Marquand-Zion School District / 1,395 |
| 31. | $34,275 | Twin Rivers R-X School District / 6,224 |
| 32. | $33,355 | Greenville R-II School District / 5,349 |
| 33. | $32,826 | Naylor R-II School District / 1,736 |
| 34. | $32,674 | Campbell R-II School District / 3,649 |
| 35. | $32,344 | Zalma R-V School District / 1,578 |
| 36. | $32,230 | North Pemiscot County R-I School District / 1,752 |
| 37. | $32,228 | New Madrid County R-I School District / 9,242 |
| 38. | $31,669 | Kennett 39 School District / 11,138 |
| 39. | $31,656 | South Pemiscot Schools / 3,479 |
| 40. | $31,588 | Woodland R-IV School District / 5,825 |
| 41. | $31,524 | Clearwater R-I School District / 6,980 |
| 42. | $31,210 | Gideon School District / 1,660 |
| 43. | $31,073 | Piggott School District / 5,509 |
| 44. | $30,750 | East Carter County R-II School District / 4,031 |
| 45. | $30,679 | Doniphan R-I School District / 10,407 |
| 46. | $30,375 | Scott County R-II School District / 3,581 |
| 47. | $30,125 | Clarkton C-4 School District / 1,916 |
| 48. | $29,397 | Malden R-I School District / 6,108 |
| 49. | $29,018 | Ripley County R-IV School District / 783 |
| 50. | $28,906 | Southland School District / 2,027 |
| 51. | $28,424 | Corning Public Schools / 6,943 |
| 52. | $26,781 | Caruthersville School District / 6,004 |
| 53. | $23,351 | Hayti R-II School District / 3,750 |
Please note that we only rank locations with 'Median Household Income' data. The rank above might not be a complete list. Locations without 'Median Household Income' data are not listed.
