| Rank | Total Population ▼ | School District / Population |
| 1. | 143,629 | Sioux Falls School District 49-5 / 143,629 |
| 2. | 91,522 | Rapid City School District 51-4 / 91,522 |
| 3. | 30,759 | Aberdeen School District 06-1 / 30,759 |
| 4. | 25,450 | Brookings School District 05-1 / 25,450 |
| 5. | 25,013 | Watertown School District 14-4 / 25,013 |
| 6. | 20,134 | Yankton School District 63-3 / 20,134 |
| 7. | 18,417 | Mitchell School District 17-2 / 18,417 |
| 8. | 18,211 | Meade School District 46-1 / 18,211 |
| 9. | 16,064 | Pierre School District 32-2 / 16,064 |
| 10. | 16,026 | Brandon Valley School District 49-2 / 16,026 |
| 11. | 15,963 | Harrisburg School District 41-2 / 15,963 |
| 12. | 15,452 | Spearfish School District 40-2 / 15,452 |
| 13. | 15,123 | Huron School District 02-2 / 15,123 |
| 14. | 13,586 | Shannon County School District 65-1 / 13,586 |
| 15. | 12,235 | Vermillion School District 13-1 / 12,235 |
| 16. | 11,829 | Douglas School District 51-1 / 11,829 |
| 17. | 9,612 | Todd County School District 66-1 / 9,612 |
| 18. | 8,762 | Madison Central School District 39-2 / 8,762 |
| 19. | 7,983 | Custer School District 16-1 / 7,983 |
| 20. | 7,962 | Belle Fourche School District 09-1 / 7,962 |
| 21. | 7,853 | Sisseton School District 54-2 / 7,853 |
| 22. | 6,625 | Lead-Deadwood School District 40-1 / 6,625 |
| 23. | 6,278 | Dakota Valley School District 61-8 / 6,278 |
| 24. | 6,058 | West Central School District 49-7 / 6,058 |
| 25. | 6,044 | Chamberlain School District 07-1 / 6,044 |
| 26. | 5,988 | Lennox School District 41-4 / 5,988 |
| 27. | 5,954 | Hot Springs School District 23-2 / 5,954 |
| 28. | 5,743 | Milbank School District 25-4 / 5,743 |
| 29. | 5,582 | Canton School District 41-1 / 5,582 |
| 30. | 5,508 | Dell Rapids School District 49-3 / 5,508 |
| 31. | 5,408 | Tea Area School District 41-5 / 5,408 |
| 32. | 5,024 | Tri-Valley School District 49-6 / 5,024 |
| 33. | 4,830 | Eagle Butte School District 20-1 / 4,830 |
| 34. | 4,791 | Bon Homme School District 04-2 / 4,791 |
| 35. | 4,660 | Winner School District 59-2 / 4,660 |
| 36. | 4,318 | Mobridge-Pollock School District 62-6 / 4,318 |
| 37. | 3,907 | Elk Point-Jefferson School District 61-7 / 3,907 |
| 37. | 3,907 | Flandreau School District 50-3 / 3,907 |
| 39. | 3,830 | Wagner School District 11-4 / 3,830 |
| 40. | 3,587 | Groton Area School District 06-6 / 3,587 |
| 41. | 3,549 | Redfield School District 56-4 / 3,549 |
| 42. | 3,431 | Bennett County School District 03-1 / 3,431 |
| 43. | 3,381 | Beresford School District 61-2 / 3,381 |
| 44. | 3,327 | Deuel School District 19-4 / 3,327 |
| 45. | 3,325 | Sioux Valley School District 05-5 / 3,325 |
| 46. | 3,314 | Hamlin School District 28-3 / 3,314 |
| 47. | 3,298 | Kadoka School District 35-2 / 3,298 |
| 48. | 3,196 | Hill City School District 51-2 / 3,196 |
| 49. | 3,157 | Platte-Geddes School District 11-5 / 3,157 |
| 50. | 3,149 | Britton-Hecla School District 45-4 / 3,149 |
| 51. | 3,107 | Miller Area School District 29-4 / 3,107 |
| 52. | 3,038 | Webster School District 18-4 / 3,038 |
| 53. | 2,974 | Lyman School District 42-1 / 2,974 |
| 54. | 2,966 | Stanley County School District 57-1 / 2,966 |
| 55. | 2,950 | Parkston School District 33-3 / 2,950 |
| 56. | 2,566 | Clark School District 12-2 / 2,566 |
| 57. | 2,474 | Garretson School District 49-4 / 2,474 |
| 58. | 2,462 | Freeman School District 33-1 / 2,462 |
| 59. | 2,456 | McLaughlin School District 15-2 / 2,456 |
| 60. | 2,413 | Ipswich School District 22-6 / 2,413 |
| 61. | 2,375 | Howard School District 48-3 / 2,375 |
| 62. | 2,300 | McCook Central School District 43-7 / 2,300 |
| 63. | 2,273 | Alcester-Hudson School District 61-1 / 2,273 |
| 64. | 2,242 | Andes Central School District 11-1 / 2,242 |
| 65. | 2,206 | Newell School District 09-2 / 2,206 |
| 66. | 2,190 | Gregory School District 26-4 / 2,190 |
| 67. | 2,124 | Lemmon School District 52-4 / 2,124 |
| 68. | 2,112 | Faulkton School District 24-4 / 2,112 |
| 69. | 2,024 | Irene-Wakonda School District 13-3 / 2,024 |
| 70. | 2,013 | Parker School District 60-4 / 2,013 |
| 71. | 1,967 | Baltic School District 49-1 / 1,967 |
| 72. | 1,915 | Agar-Blunt-Onida School District 58-3 / 1,915 |
| 72. | 1,915 | Arlington School District 38-1 / 1,915 |
| 74. | 1,902 | Deubrook School District 05-6 / 1,902 |
| 75. | 1,884 | Wessington Springs School District 36-2 / 1,884 |
| 76. | 1,870 | Scotland School District 04-3 / 1,870 |
| 77. | 1,854 | Hanson School District 30-1 / 1,854 |
| 78. | 1,821 | Highmore-Harrold School District 34-2 / 1,821 |
| 79. | 1,800 | Northwestern Area School District 56-7 / 1,800 |
| 80. | 1,790 | Dupree School District 64-2 / 1,790 |
| 81. | 1,782 | White River School District 47-1 / 1,782 |
| 82. | 1,727 | De Smet School District 38-2 / 1,727 |
| 83. | 1,697 | Haakon School District 27-1 / 1,697 |
| 84. | 1,692 | Chester School District 39-1 / 1,692 |
| 85. | 1,663 | Colman-Egan School District 50-5 / 1,663 |
| 86. | 1,594 | Selby School District 62-5 / 1,594 |
| 87. | 1,589 | Estelline School District 28-2 / 1,589 |
| 88. | 1,573 | Marion School District 60-3 / 1,573 |
| 89. | 1,540 | Tripp-Delmont School District 33-5 / 1,540 |
| 89. | 1,540 | Wilmot School District 54-7 / 1,540 |
| 91. | 1,536 | Menno School District 33-2 / 1,536 |
| 92. | 1,510 | Centerville School District 60-1 / 1,510 |
| 93. | 1,497 | Wall School District 51-5 / 1,497 |
| 94. | 1,474 | Timber Lake School District 20-3 / 1,474 |
| 95. | 1,467 | Elkton School District 05-3 / 1,467 |
| 96. | 1,461 | Kimball School District 07-2 / 1,461 |
| 97. | 1,419 | Viborg School District 60-5 / 1,419 |
| 98. | 1,394 | Castlewood School District 28-1 / 1,394 |
| 99. | 1,359 | Waubay School District 18-3 / 1,359 |
| 100. | 1,353 | Gettysburg School District 53-1 / 1,353 |
| 101. | 1,335 | Hitchcock-Tulare School District 56-6 / 1,335 |
| 102. | 1,317 | Burke School District 26-2 / 1,317 |
| 103. | 1,305 | Eureka School District 44-1 / 1,305 |
| 104. | 1,281 | Plankinton School District 01-1 / 1,281 |
| 105. | 1,257 | Wolsey-Wessington School District 02-6 / 1,257 |
| 106. | 1,255 | Harding County School District 31-1 / 1,255 |
| 107. | 1,241 | Corsica School District 21-2 / 1,241 |
| 108. | 1,227 | Iroquois School District 02-3 / 1,227 |
| 109. | 1,217 | Woonsocket School District 55-4 / 1,217 |
| 110. | 1,215 | Sanborn Central School District 55-5 / 1,215 |
| 111. | 1,214 | Leola School District 44-2 / 1,214 |
| 112. | 1,212 | Colome Consolidated School District 59-3 / 1,212 |
| 113. | 1,207 | Canistota School District 43-1 / 1,207 |
| 114. | 1,195 | Langford School District 45-2 / 1,195 |
| 115. | 1,174 | Lake Preston School District 38-3 / 1,174 |
| 116. | 1,167 | New Underwood School District 51-3 / 1,167 |
| 117. | 1,158 | Avon School District 04-1 / 1,158 |
| 118. | 1,130 | Warner School District 06-5 / 1,130 |
| 119. | 1,127 | Hoven School District 53-2 / 1,127 |
| 120. | 1,120 | Montrose School District 43-2 / 1,120 |
| 121. | 1,100 | Edgemont School District 23-1 / 1,100 |
| 122. | 1,060 | Willow Lake School District 12-3 / 1,060 |
| 123. | 1,058 | Waverly School District 14-5 / 1,058 |
| 124. | 1,054 | Armour School District 21-1 / 1,054 |
| 125. | 1,030 | Gayville-Volin School District 63-1 / 1,030 |
| 126. | 1,028 | Rosholt School District 54-4 / 1,028 |
| 127. | 1,021 | Edmunds Central School District 22-5 / 1,021 |
| 128. | 998 | Mount Vernon School District 17-3 / 998 |
| 129. | 993 | Jones County School District 37-3 / 993 |
| 130. | 970 | Grant-Deuel School District 25-3 / 970 |
| 131. | 965 | Frederick Area School District 06-2 / 965 |
| 132. | 946 | Hurley School District 60-2 / 946 |
| 133. | 912 | Bison School District 52-1 / 912 |
| 134. | 876 | Bridgewater School District 43-6 / 876 |
| 135. | 875 | Oldham-Ramona School District 39-5 / 875 |
| 136. | 857 | South Central School District 26-5 / 857 |
| 137. | 851 | McIntosh School District 15-1 / 851 |
| 138. | 849 | Doland School District 56-2 / 849 |
| 139. | 836 | Florence School District 14-1 / 836 |
| 140. | 809 | Faith School District 46-2 / 809 |
| 141. | 788 | Ethan School District 17-1 / 788 |
| 142. | 758 | Bowdle School District 22-1 / 758 |
| 143. | 747 | Emery School District 30-2 / 747 |
| 144. | 735 | Roslyn School District 18-2 / 735 |
| 145. | 734 | Big Stone City School District 25-1 / 734 |
| 146. | 729 | Stickney School District 01-2 / 729 |
| 147. | 723 | White Lake School District 01-3 / 723 |
| 148. | 688 | Herreid School District 10-1 / 688 |
| 149. | 620 | Summit School District 54-6 / 620 |
| 150. | 578 | Rutland School District 39-4 / 578 |
| 151. | 534 | Henry School District 14-2 / 534 |
| 152. | 467 | Smee School District 15-3 / 467 |
| 153. | 355 | Oelrichs School District 23-3 / 355 |
| 154. | 305 | Greater Hoyt School District 61-4 / 305 |
| 155. | 261 | Elk Mountain School District 16-2 / 261 |
| 156. | 112 | Greater Scott School District 61-5 / 112 |
Please note that we only rank locations with 'Total Population' data. The rank above might not be a complete list. Locations without 'Total Population' data are not listed.
