| Rank | Indian Population Percentage ▼ | School District / Population |
| 1. | 1.0% | Lexington School District 5 / 88,313 |
| 2. | 0.9% | York School District 4 / 38,688 |
| 3. | 0.8% | Spartanburg School District 2 / 51,997 |
| 4. | 0.6% | Greenville County School District / 444,979 |
| 5. | 0.5% | Spartanburg School District 6 / 59,872 |
| 6. | 0.5% | Richland School District 1 / 195,966 |
| 7. | 0.5% | Sumter School District 17 / 49,864 |
| 8. | 0.4% | Georgetown County School District / 60,235 |
| 8. | 0.4% | Orangeburg School District 5 / 50,005 |
| 10. | 0.4% | Richland School District 2 / 108,900 |
| 11. | 0.4% | Anderson School District 5 / 75,620 |
| 12. | 0.4% | Pickens County School District / 116,092 |
| 13. | 0.4% | Lexington School District 1 / 106,932 |
| 14. | 0.3% | Spartanburg School District 7 / 54,475 |
| 15. | 0.3% | Florence School District 1 / 92,226 |
| 16. | 0.3% | York School District 3 / 108,583 |
| 17. | 0.3% | Florence School District 3 / 20,769 |
| 18. | 0.3% | York School District 2 / 31,589 |
| 18. | 0.3% | Laurens School District 55 / 39,947 |
| 20. | 0.3% | Charleston County School District / 345,714 |
| 21. | 0.2% | Beaufort County School District / 145,930 |
| 21. | 0.2% | Lexington School District 3 / 13,485 |
| 23. | 0.2% | Cherokee County School District / 52,016 |
| 23. | 0.2% | Lancaster County School District / 73,725 |
| 25. | 0.2% | Greenwood School District 50 / 57,633 |
| 25. | 0.2% | Berkeley County School District / 163,328 |
| 27. | 0.2% | Horry County School District / 248,601 |
| 28. | 0.2% | Marlboro County School District / 28,571 |
| 29. | 0.2% | Darlington County School District / 66,771 |
| 30. | 0.1% | Spartanburg School District 3 / 17,604 |
| 30. | 0.1% | Aiken County School District / 155,496 |
| 32. | 0.1% | Anderson School District 1 / 47,632 |
| 33. | 0.1% | Oconee County School District / 70,507 |
| 33. | 0.1% | Richland County School District 2 within Fort Jackson / 14,220 |
| 33. | 0.1% | Fort Jackson Schools / 14,220 |
| 36. | 0.1% | Newberry County School District / 37,992 |
| 36. | 0.1% | Dorchester School District 2 / 105,973 |
| 38. | 0.1% | Name N/A / 16,089 |
| 38. | 0.1% | Edgefield County School District / 25,469 |
| 38. | 0.1% | Chesterfield County School District / 42,876 |
| 38. | 0.1% | Lexington School District 2 / 61,390 |
| 38. | 0.1% | Dillon School District 2 / 18,186 |
| 38. | 0.1% | Sumter School District 2 / 54,577 |
| 44. | 0.1% | McCormick County School District / 10,087 |
| 45. | 0.1% | Kershaw County School District / 58,176 |
| 45. | 0.1% | Spartanburg School District 1 / 30,279 |
| 47. | 0.1% | Florence School District 2 / 6,661 |
| 48. | 0.0% | Union County School District / 27,800 |
| 49. | 0.0% | Spartanburg School District 5 / 38,566 |
| 50. | 0.0% | Chester County School District / 32,666 |
Please note that we only rank locations with 'Indian Population Percentage' data. The rank above might not be a complete list. Locations without 'Indian Population Percentage' data are not listed.
*ACS stands for U.S. Census American Community Survey. According to the U.S. Census, if the date is a range, you can interpret the data as an average of the period of time.
