| Rank | Median Household Income ▼ | School District / Population |
| 1. | $58,654 | Liberty Community Unit School District 2 / 3,463 |
| 2. | $53,889 | Harrisburg R-VIII School District / 3,112 |
| 3. | $51,827 | Renick R-V School District / 1,524 |
| 4. | $51,731 | Payson Community Unit School District 1 / 3,569 |
| 5. | $51,181 | Pike County R-III School District / 2,797 |
| 6. | $49,702 | Palmyra R-I School District / 6,488 |
| 7. | $49,309 | Sturgeon R-V School District / 3,532 |
| 8. | $48,750 | Boncl R-X School District / 451 |
| 9. | $48,271 | Centralia R-VI School District / 7,640 |
| 10. | $47,250 | Middle Grove C-1 School District / 646 |
| 11. | $46,806 | Community R-VI School District / 2,268 |
| 12. | $46,543 | Boone County R-IV School District / 6,889 |
| 13. | $46,382 | Silex R-I School District / 2,598 |
| 14. | $46,104 | Bowling Green R-I School District / 11,991 |
| 15. | $44,896 | Community Unit School District 4 / 4,160 |
| 16. | $44,732 | Shelby County C-1 School District / 2,153 |
| 17. | $44,589 | North Callaway R-I School District / 6,700 |
| 18. | $43,836 | Marion County R-II School District / 1,319 |
| 19. | $43,510 | Northeast Randolph County R-IV School District / 1,860 |
| 20. | $43,125 | Camp Point Community Unit School District 3 / 4,857 |
| 21. | $42,865 | Canton School District / 4,835 |
| 22. | $42,585 | Ralls County R-II School District / 5,779 |
| 23. | $42,191 | Monroe City R-I School District / 4,716 |
| 24. | $42,172 | Quincy School District 172 / 50,932 |
| 25. | $41,250 | Callao C-8 School District / 684 |
| 26. | $40,652 | Pleasant Hill Community Unit School District 3 / 2,195 |
| 27. | $40,451 | Mexico 59 School District / 14,740 |
| 28. | $40,435 | Lewis County C-1 School District / 6,182 |
| 29. | $40,394 | Montgomery County R-II School District / 8,621 |
| 30. | $39,702 | Bevier C-4 School District / 1,539 |
| 31. | $39,701 | Western Community Unit School District 12 / 3,772 |
| 32. | $39,519 | Madison C-3 School District / 1,471 |
| 33. | $39,000 | Higbee R-VIII School District / 1,422 |
| 34. | $38,929 | Hannibal School District / 22,444 |
| 35. | $38,846 | Westran R-I School District / 3,774 |
| 36. | $38,023 | Wellsville-Middletown R-I School District / 2,846 |
| 37. | $37,262 | Macon County R-I School District / 8,353 |
| 38. | $37,040 | Paris R-II School District / 3,480 |
| 39. | $36,944 | Holliday C-2 School District / 499 |
| 40. | $35,766 | Van-Far School District / 5,748 |
| 41. | $35,355 | Louisiana R-II School District / 4,167 |
| 42. | $33,804 | Shelby County R-IV School District / 4,408 |
| 43. | $33,750 | Atlanta C-3 Schools / 1,316 |
| 44. | $33,055 | Moberly School District / 16,330 |
| 45. | $33,029 | Knox County R-I School District / 4,089 |
| 46. | $30,991 | La Plata R-II School District / 2,717 |
Please note that we only rank locations with 'Median Household Income' data. The rank above might not be a complete list. Locations without 'Median Household Income' data are not listed.
*ACS stands for U.S. Census American Community Survey. According to the U.S. Census, if the date is a range, you can interpret the data as an average of the period of time.
