| Rank | Median Household Income ▼ | School District / Population |
| 1. | $57,917 | Kelso C-7 School District / 2,030 |
| 2. | $53,409 | Leopold R-III School District / 1,036 |
| 3. | $52,148 | Nell Holcomb R-IV School District / 2,959 |
| 4. | $50,000 | Altenburg 48 School District / 1,159 |
| 5. | $49,551 | Jackson R-II School District / 28,804 |
| 6. | $48,860 | Meadow Heights R-II School District / 3,822 |
| 7. | $47,587 | Chester Community Unit School District 139 / 11,196 |
| 8. | $45,370 | Ste. Genevieve County R-II School District / 15,248 |
| 9. | $44,946 | Perry County 32 School District / 17,662 |
| 10. | $44,775 | Scott County R-IV School District / 5,546 |
| 11. | $43,849 | Sunrise R-IX School District / 3,393 |
| 12. | $43,822 | Farmington R-7 School District / 27,218 |
| 13. | $43,431 | Oran R-III School District / 2,306 |
| 14. | $42,847 | Oak Ridge R-VI School District / 2,011 |
| 15. | $42,292 | Prairie du Rocher Community Consolidated School District 134 / 868 |
| 15. | $42,292 | Chester Non-High School District 122 / 868 |
| 17. | $41,250 | Delta R-V School District / 2,524 |
| 18. | $40,800 | North St. Francis County R-I School District / 19,721 |
| 19. | $40,519 | Valley R-VI School District / 2,878 |
| 20. | $40,259 | Richland R-I School District / 1,930 |
| 21. | $39,936 | Cape Girardeau 63 School District / 37,975 |
| 22. | $39,792 | Bell City R-II School District / 1,409 |
| 23. | $38,796 | Scott City R-I School District / 5,550 |
| 24. | $38,781 | Dexter R-XI School District / 12,529 |
| 25. | $38,739 | West St. Francis County R-IV School District / 5,527 |
| 26. | $37,778 | Shawnee Community Unit School District 84 / 3,248 |
| 27. | $36,629 | Scott County R-II School District / 3,782 |
| 28. | $36,150 | Puxico R-VIII School District / 4,836 |
| 29. | $35,528 | Central R-III School District / 11,577 |
| 30. | $34,728 | Bismarck R-V School District / 3,596 |
| 31. | $34,615 | Marquand-Zion School District / 1,643 |
| 32. | $34,369 | Poplar Bluff R-I School District / 32,787 |
| 33. | $33,701 | Fredericktown R-I School District / 10,506 |
| 34. | $33,086 | Southern Reynolds County R-IV School District / 3,105 |
| 35. | $32,571 | Advance R-IV School District / 3,233 |
| 36. | $32,303 | Scott County Central Schools / 2,006 |
| 37. | $32,155 | Belleview R-III School District / 1,251 |
| 38. | $32,076 | Arcadia Valley R-II School District / 6,099 |
| 39. | $31,930 | Clearwater R-I School District / 7,087 |
| 40. | $31,777 | Potosi R-III School District / 12,832 |
| 41. | $31,691 | Lesterville R-IV School District / 1,169 |
| 42. | $31,345 | Bloomfield School District / 4,477 |
| 43. | $30,125 | Zalma R-V School District / 1,792 |
| 44. | $29,402 | East Carter County R-II School District / 4,328 |
| 45. | $28,094 | Twin Rivers R-X School District / 5,557 |
| 46. | $28,048 | South Iron County R-I School District / 2,060 |
| 47. | $27,939 | Greenville R-II School District / 5,211 |
| 48. | $27,500 | Woodland R-IV School District / 5,413 |
| 49. | $24,000 | Centerville R-I School District / 826 |
Please note that we only rank locations with 'Median Household Income' data. The rank above might not be a complete list. Locations without 'Median Household Income' data are not listed.
*ACS stands for U.S. Census American Community Survey. According to the U.S. Census, if the date is a range, you can interpret the data as an average of the period of time.
