| Rank | Median Household Income ▼ | School District / Population |
| 1. | $57,917 | Kelso C-7 School District / 2,030 |
| 2. | $55,750 | Lick Creek Community Consolidated School District 16 / 1,080 |
| 3. | $52,148 | Nell Holcomb R-IV School District / 2,959 |
| 4. | $49,763 | McCracken County School District / 44,257 |
| 5. | $48,694 | Giant City Community Consolidated School District 130 / 2,344 |
| 6. | $44,979 | Carterville Community Unit School District 5 / 10,959 |
| 7. | $44,775 | Scott County R-IV School District / 5,546 |
| 8. | $44,617 | Crab Orchard Community Unit School District 3 / 2,359 |
| 9. | $44,160 | Goreville Community Unit School District 1 / 2,984 |
| 10. | $44,125 | Cypress School District 64 / 901 |
| 11. | $43,326 | Marshall County School District / 31,386 |
| 12. | $42,632 | Cobden School Unit District 17 / 3,705 |
| 13. | $42,079 | Lyon County School District / 8,367 |
| 14. | $41,534 | Johnston City Community Unit School District 1 / 8,074 |
| 15. | $41,415 | Massac Unit School District 1 / 13,835 |
| 16. | $41,228 | Ballard County School District / 8,225 |
| 17. | $41,225 | Marion Community Unit School District 2 / 27,375 |
| 18. | $40,156 | Anna Jonesboro Community High School District 81 / 11,336 |
| 19. | $39,936 | Cape Girardeau 63 School District / 37,975 |
| 20. | $39,672 | Pope County Community Unit School District 1 / 4,426 |
| 21. | $39,558 | Graves County School District / 27,305 |
| 22. | $39,482 | Gallatin Community Unit School District 7 / 5,582 |
| 23. | $39,329 | New Simpson Hill Consolidated District 32 / 3,182 |
| 24. | $39,220 | Murray Independent School District / 10,779 |
| 25. | $39,182 | Calloway County School District / 25,984 |
| 26. | $39,115 | Joppa-Maple Grove Unit District 38 / 1,520 |
| 27. | $39,075 | Livingston County School District / 9,514 |
| 28. | $38,804 | Anna Community Consolidated School District 37 / 7,124 |
| 29. | $38,796 | Scott City R-I School District / 5,550 |
| 30. | $38,553 | Dongola School Unit District 66 / 1,849 |
| 31. | $38,393 | Egyptian Community Unit School District 5 / 3,902 |
| 32. | $38,051 | Vienna High School District 133 / 9,730 |
| 33. | $37,778 | Shawnee Community Unit School District 84 / 3,248 |
| 34. | $37,730 | Jonesboro Community Consolidated School District 43 / 3,132 |
| 35. | $37,613 | Harrisburg Community Unit School District 3 / 12,869 |
| 36. | $37,165 | Fulton County School District / 3,692 |
| 37. | $37,034 | Century Community Unit School District 100 / 2,852 |
| 38. | $36,319 | Vienna School District 55 / 5,124 |
| 39. | $36,140 | Herrin Community Unit School District 4 / 16,062 |
| 40. | $35,289 | Caldwell County School District / 12,934 |
| 41. | $34,943 | East Prairie R-II School District / 5,655 |
| 42. | $34,623 | Crittenden County School District / 9,313 |
| 43. | $33,909 | Carlisle County School District / 5,126 |
| 44. | $33,694 | Eldorado Community Unit School District 4 / 7,364 |
| 45. | $32,694 | Unity Point Community Consolidated School District 140 / 5,451 |
| 46. | $31,836 | Hickman County School District / 4,949 |
| 47. | $30,646 | Carrier Mills-Stonefort Community Unit School District / 2,841 |
| 48. | $30,547 | Galatia Community Unit School District 1 / 2,306 |
| 49. | $29,000 | Buncombe Consolidated School District 43 / 523 |
| 50. | $28,602 | Meridian Community Unit School District 101 / 3,511 |
| 51. | $28,082 | Carbondale Community High School District 165 / 37,283 |
| 52. | $27,578 | Hardin County Community Unit School District 1 / 4,402 |
| 53. | $26,693 | Fulton Independent School District / 3,166 |
| 54. | $26,638 | Mayfield Independent School District / 9,653 |
| 55. | $26,457 | Paducah Independent School District / 20,960 |
| 56. | $26,203 | Charleston R-I School District / 8,488 |
| 57. | $22,892 | Cairo Community Unit School District 1 / 3,096 |
| 58. | $22,779 | Carbondale Elementary School District 95 / 27,628 |
Please note that we only rank locations with 'Median Household Income' data. The rank above might not be a complete list. Locations without 'Median Household Income' data are not listed.
*ACS stands for U.S. Census American Community Survey. According to the U.S. Census, if the date is a range, you can interpret the data as an average of the period of time.
