| Rank | House Median Value ▼ | School District / Population |
| 1. | $160,700 | Kelso C-7 School District / 2,030 |
| 2. | $154,700 | Unity Point Community Consolidated School District 140 / 5,451 |
| 3. | $146,600 | Jackson R-II School District / 28,804 |
| 4. | $135,200 | Giant City Community Consolidated School District 130 / 2,344 |
| 5. | $129,300 | Lick Creek Community Consolidated School District 16 / 1,080 |
| 6. | $128,000 | Nell Holcomb R-IV School District / 2,959 |
| 6. | $128,000 | Cape Girardeau 63 School District / 37,975 |
| 8. | $125,400 | Perry County 32 School District / 17,662 |
| 9. | $123,800 | Leopold R-III School District / 1,036 |
| 10. | $103,000 | Altenburg 48 School District / 1,159 |
| 11. | $100,400 | Scott County R-IV School District / 5,546 |
| 12. | $98,500 | Meadow Heights R-II School District / 3,822 |
| 13. | $97,000 | Scott City R-I School District / 5,550 |
| 14. | $95,000 | Dongola School Unit District 66 / 1,849 |
| 14. | $95,000 | Woodland R-IV School District / 5,413 |
| 16. | $94,900 | Poplar Bluff R-I School District / 32,787 |
| 17. | $94,200 | Cobden School Unit District 17 / 3,705 |
| 17. | $94,200 | Bloomfield School District / 4,477 |
| 19. | $93,800 | Sikeston School District / 20,780 |
| 20. | $93,600 | Dexter R-XI School District / 12,529 |
| 21. | $90,200 | Oran R-III School District / 2,306 |
| 22. | $87,600 | Scott County R-II School District / 3,782 |
| 23. | $85,300 | Anna Jonesboro Community High School District 81 / 11,336 |
| 24. | $84,700 | Fredericktown R-I School District / 10,506 |
| 25. | $84,500 | Buncombe Consolidated School District 43 / 523 |
| 26. | $84,300 | Jonesboro Community Consolidated School District 43 / 3,132 |
| 27. | $84,000 | Murphysboro Community Unit School District 186 / 15,300 |
| 28. | $81,700 | Anna Community Consolidated School District 37 / 7,124 |
| 29. | $80,400 | Delta R-V School District / 2,524 |
| 30. | $79,900 | Oak Ridge R-VI School District / 2,011 |
| 31. | $78,600 | Marquand-Zion School District / 1,643 |
| 32. | $78,100 | Portageville School District / 4,060 |
| 32. | $78,100 | Ballard County School District / 8,225 |
| 34. | $76,700 | Joppa-Maple Grove Unit District 38 / 1,520 |
| 35. | $76,500 | Advance R-IV School District / 3,233 |
| 36. | $75,100 | Bernie School District / 3,497 |
| 37. | $72,400 | East Prairie R-II School District / 5,655 |
| 38. | $68,400 | Cypress School District 64 / 901 |
| 39. | $67,400 | Carlisle County School District / 5,126 |
| 40. | $66,900 | Scott County Central Schools / 2,006 |
| 41. | $65,900 | Zalma R-V School District / 1,792 |
| 42. | $65,400 | Puxico R-VIII School District / 4,836 |
| 43. | $64,500 | Egyptian Community Unit School District 5 / 3,902 |
| 44. | $64,400 | Bell City R-II School District / 1,409 |
| 45. | $63,600 | Hickman County School District / 4,949 |
| 46. | $63,500 | New Madrid County R-I School District / 9,827 |
| 47. | $62,300 | Twin Rivers R-X School District / 5,557 |
| 48. | $62,100 | Charleston R-I School District / 8,488 |
| 49. | $61,700 | Richland R-I School District / 1,930 |
| 50. | $61,400 | Risco R-II School District / 673 |
| 51. | $60,300 | Shawnee Community Unit School District 84 / 3,248 |
| 52. | $58,600 | Campbell R-II School District / 3,626 |
| 53. | $58,300 | Malden R-I School District / 6,348 |
| 54. | $58,100 | Fulton County School District / 3,692 |
| 55. | $56,300 | Century Community Unit School District 100 / 2,852 |
| 56. | $55,200 | Greenville R-II School District / 5,211 |
| 57. | $47,600 | Gideon School District / 1,711 |
| 58. | $42,500 | Meridian Community Unit School District 101 / 3,511 |
| 59. | $41,300 | Clarkton C-4 School District / 1,783 |
| 60. | $33,300 | Cairo Community Unit School District 1 / 3,096 |
Please note that we only rank locations with 'House Median Value' data. The rank above might not be a complete list. Locations without 'House Median Value' data are not listed.
*ACS stands for U.S. Census American Community Survey. According to the U.S. Census, if the date is a range, you can interpret the data as an average of the period of time.
